Following medical school, he completed an internal medicine residency at the University of Alabama at Birmingham. He then went to Johns Hopkins Hospital for his medical oncology fellowship, which focused on translational research in the development of novel therapies for pancreatic cancer. Prior to his present position at Harvard Medical/Massachusetts General Hospital, Dr. Weekes served on the faculty at the University of Colorado School of Medicine - Anschutz Medical Campus in Denver in the division of medical oncology. Dr. Weekes' primary focus is on clinical and translational research in patients with pancreatic cancer. The goal of his research group is to incorporate biologic principles into the treatment of patients with pancreatic cancer. He works with basic scientists to integrate targeted therapies and biomarkers of disease response into clinical trial development. In addition to his work in pancreas cancer, Dr. Weekes focuses on early drug development for gastrointestinal malignancies. His clinical interests include pancreatic cancer, colon and rectal cancer, as well as liver cancers, including cholangiocarcinoma and hepatocellular carcinoma. He treats patients with a variety of cancer types, including colorectal, esophageal, gallbladder, gastrointestinal, liver and stomach.